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Mitochondrial

Creatine

Also known as: Creatine Monohydrate

Strong Evidence500+ human studies

The most evidence-backed performance supplement. Increasingly recognised for cognitive benefits and longevity effects beyond muscle.

Mechanism of Action

Regenerates ATP via phosphocreatine system. Increases PCr stores in muscle and brain. Neuroprotective at multiple targets.

Dosage & Timing

Dose

3–5g/day (no loading needed)

When to take

Anytime — consistency matters more than timing

Evidence Scores

Evidence Quality
A+0/100
Safety Profile
A+0/100
Popularity
A+0/100