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Antioxidants

Resveratrol

Also known as: Trans-resveratrol · RSV

Emerging Evidence127+ human studies

A polyphenol that activates sirtuins (SIRT1). Famous from David Sinclair's research. Human data more mixed than animal studies.

Mechanism of Action

Activates SIRT1 and AMPK. Mimics some effects of caloric restriction. Anti-inflammatory via NF-κB inhibition.

Dosage & Timing

Dose

500mg–1g/day

When to take

With a fatty meal for absorption

Stacks Well With

NMNNRQuercetin

Caution

May interact with: blood-thinners

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Evidence Scores

Evidence Quality
C0/100
Safety Profile
A0/100
Popularity
A0/100

Goals

LongevityCardiovascularInflammation